College Football Betting Odds for Week 1 Ranked Matchups

The No. 1 ranked Georgia Bulldogs take on the No. 14 ranked Clemson Tigers as 13.5-point favorites on Saturday.
Another Week 1 ranked matchup features No. 7 ranked Notre Dame as a 3.0-point road underdog against No. 20 Texas A&M.
College football’s Week 1 wraps up with the No. 12 ranked LSU Tigers as 4.0-point favorites against the No. 23 ranked USC Trojans in Las Vegas, Nevada.

ATLANTA – Week 1 of the 2024-2025 college football season features three key matchups between top 25 ranked teams. No. 1 ranked Georgia headlines the legal sports betting slate as a 13.5-point favorite against the No. 14 ranked Clemson Tigers.

Clemson Vs Georgia Betting Odds

Team	Spread	Moneyline	Total
No. 14 Clemson Tigers	+13.5 (-115)	+410	O49.0 (-110)
No. 1 Georgia Bulldogs	-13.5 (-105)	-585	U49.0 (-110)

Mercedes-Benz Stadium in Atlanta, Georgia will host the “neutral site” game, with Bulldogs fans expected to fill the stadium. Georgia sportsbook apps set the Bulldogs team points total at 31.5 points with +105 odds for the over and -135 odds for the under.

Meanwhile, the Clemson Tigers points total stands at 17.5 points for their Week 1 matchup. That South Carolina sports betting projection has -125 odds to go under, with just -105 odds for the Tigers to score over 17.5 points.

Other CFB Week 1 Ranked Matchups Favor Texas A&M, LSU

An expected closer matchup between the Notre Dame Fighting Irish (+120) and the Texas A&M Aggies kicks off at 5:30 p.m. ET on Saturday. The Aggies have -140 odds at Texas sportsbooks to earn a top-10 win against No. 7 ranked Notre Dame at home.

Notre Dame Vs Texas A&M Betting Odds

Team	Spread	Moneyline	Total
No. 7 Notre Dame	+3.0 (-110)	+120	O46.5 (-110)
No. 20 Texas A&M	-3.0 (-110)	-140	U46.5 (-110)

Despite Texas A&M disappointing as a pre-season top 25 team the last few seasons, it hasn’t been because of their inability to win at home. Since 2021, the Aggies are 16-5 at home and 1-10 on the road including a current streak of 10 straight road losses.

With Kyle Field in College Station being one of the toughest atmospheres in college football, there’s solid value on Texas A&M’s -140 moneyline odds behind sophomore quarterback Conner Weigman. After that game concludes, legal college football betting sites offer another top-25 battle between the LSU Tigers (-185) and the USC Trojans.

LSU Vs USC Betting Odds

Team	Spread	Moneyline	Total
No. 12 LSU	-4.0 (-110)	-185	O63.5 (-110)
No. 23 USC	+4.0 (-110)	+160	U63.5 (-110)

The 63.5-point legal California sports betting total is the second-highest total of Week 1. LSU replaces 2023 Heisman Trophy winner Jayden Daniels with Garrett Nussmeier, who impressed last season in a bowl game against Wisconsin and proved he can lead the offense to plenty of points.

However, the Tigers didn’t improve much on last year’s weak secondary that now has to defend USC weapons like Zachariah Branch and more. Either team could win the game, but the over on the 63.5-point total is the best bet.

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Zachary Kelley

Zach graduated from Florida State University with a degree in Writing, Editing, and Media. Zach is interested in the legalization aspect of sports betting and enjoys participating in DFS. He has a passion for sports writing and most enjoys writing about football and baseball both professional and collegiate.