Jacksonville Jaguars vs. Indianapolis Colts

  • The Jacksonville Jaguars are 4.5-point favorites against the Indianapolis Colts in Week 1.
  • Trevor Lawrence is projected for 256.5 passing yards on Sunday.
  • The Jaguars quarterback has -130 odds to throw over 1.5 passing touchdowns.

INDIANAPOLIS – Betting odds for the Indianapolis Colts vs Jacksonville Jaguars favor the Jags by 4.5 points on the road.

A mismatch in quarterback play makes the Jaguars a heavy legal sports betting favorite with -220 moneyline odds against rookie Anthony Richardson.

Indianapolis Colts vs Jacksonville Jaguars Betting Lines

Team Spread Moneyline Total
Indianapolis Colts +4.5 (-110) +180 O45.5 (-110)
Jacksonville Jaguars -4.5 (-110) -220 U45.5 (-110)

Jacksonville ranked 10th in the NFL last season with 1.4 takeaways per game. There are -135 odds at legal NFL betting sites for Anthony Richardson to throw over 0.5 interceptions in Week 1.

Trevor Lawrence Passing Props at Indianapolis

Trevor Lawrence was efficient in his two games against the Colts last season, combining for a stat line of 45/52, 400 passing yards, three touchdowns and zero interceptions. Lawrence’s legal Florida sports betting prop for passing yards is set at 256.5 yards in Week 1.

Trevor Lawrence Passing Yards Prop

  • Over 256.5 Passing Yards -115
  • Under 256.5 Passing Yards -115

Lawrence went over 256.5 passing yards in nine of 19 games last season. However, the addition of elite route runner Calvin Ridley gives Lawrence a great opportunity to expose an inexperienced Indianapolis secondary.

Trevor Lawrence Passing Touchdowns Prop

  • Over 1.5 Passing Touchdowns -130
  • Under 1.5 Passing Touchdowns EVEN

With two second-year players and a rookie making up 75% of the Colts secondary, Trevor Lawrence should easily toss two passing touchdowns on Sunday. Lawrence went over 1.5 passing touchdowns in eight games last season, including five games with three or more passing touchdowns.

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