- Auburn is favored to win the South Region in March Madness with -155 odds.
ATLANTA – The Sweet 16 and Elite 8 continues on Friday in Atlanta with the South Region getting started where the number one overall seed in the tournament, Auburn, is set to play.
Joining Auburn in Atlanta will be their opponents, the #5 seeded Michigan Wolverines as well as the #2 Michigan State Spartans and #6 Ole Miss Rebels.
Getting into the betting side of things in the South Region, here are the odds on legal sports betting sites for each game as well as the futures odds to win the South Region and advance to the Final Four.
#5 Michigan Vs. #1 Auburn
- Moneyline: Michigan (+285) vs. Auburn (-370)
- Spread: Auburn -8
- Total: 151.5
#6 Ole Miss Vs. #2 Michigan State
- Moneyline: Ole Miss (+130) vs. Michigan State (-150)
- Spread: Michigan State -3
- Total: 144
2025 March Madness South Region Odds
- #1 Auburn -155
- #2 Michigan State +350
- #5 Michigan +550
- #6 Mississippi +750
March Madness South Region Betting Trends
When betting on either of these four teams in the South Region, bettors can look to betting trends to see just how profitable each of them have been through the tournament. The two main betting trends that bettors keep in mind are their numbers against the spread as well as their over/under numbers.
South Region Against The Spread Records
- Michigan State: 2-0
- Michigan: 2-0
- Mississippi: 2-0
- Auburn: 1-1
South Region Over/Under Records
- Auburn: 1-1
- Michigan: 1-1
- Mississippi: 1-1
- Michigan State: 0-2
Bet On March Madness In Atlanta & In Georgia
There are several options when it comes to sportsbooks in Atlanta to bet on March Madness and all of them are available online. Online sports betting is legal in Georgia through offshore online betting sites as they accept players from the Peach State and have done so for several years. Those around the state can also use one of these Georgia sports betting sites.
Advertising Disclosure
In order to provide you with the best independent sports betting news and content LegalSportsBetting.com may receive a commission from partners when you make a purchase through a link on our site.
News tags: Atlanta | Auburn | Auburn Tigers | basketball | CBB | College Basketball | Elite 8 | March Madness | Michigan | Michigan State | Michigan State Spartans | Michigan Wolverines | Ole Miss | Ole Miss Rebels | Sweet 16

Samuel has been writing professionally for 4 years. He comes from a sports writing background where he enjoys writing mostly about basketball and football both professional and collegiate. He is a recent graduate of Florida State University where he majored in Editing, Writing and Media with a minor in Communications. During his free time, you can find him watching or playing sports as well as playing videogames and listening to music.