NFL Preseason Odds: Texans, Bills Best Bets of Week 1 Action

The Houston Texans are 2.0-point favorites (-110) against the New England Patriots in the 2023-2024 NFL preseason opener for Week 1.
A surprising Week 1 underdog is the Buffalo Bills (+2.5) to the Indianapolis Colts.
Both Houston and Buffalo have value to cover their spreads based on preseason records from previous seasons.

HOUSTON – Betting odds are available for the opening weekend of NFL preseason football. Although the competition and skills won’t mirror the NFL regular season, plenty of betting value is available on the Houston Texans and Buffalo Bills.

The Houston Texans are slight 2.0-point favorites at legal online sportsbooks against the New England Patriots in the first preseason game of Week 1.

Houston Texans Vs New England Patriots Betting Odds

Team:	Spread:	Total:
Houston Texans	-2.0 (-110)	O38.5 (-110)
New England Patriots	+2.0 (-110)	U38.5 (-110)

Pre-season odds at legal NFL betting sites are so fresh they don’t even have moneyline odds yet. Still, betting on Houston’s spread (-110) against the New England Patriots is a valuable wager considering the Texans’ recent preseason success.

The Houston Texans are 5-1 in the preseason over the last two years. In last year’s preseason, the Texans were 3-0 while the Patriots went 1-2.

Houston has an advantage on the spread, but the over at 38.5 points also has value with -110 odds. The Texans will make sure to get future starting quarterback C.J. Stroud plenty of reps, but former starters Davis Mills and Case Keenum can contribute towards the over.

Houston Texans bettors can capitalize on the value at legal Texas online sportsbook sites for their solid quarterback room and successful preseason history. The Texans and Patriots clash at 7 p.m. ET on Thursday.

Indianapolis Colts Vs Buffalo Bills

Another valuable legal sports betting opportunity for the preseason’s opening weekend is on the Buffalo Bills. The Bills are surprising underdogs to Anthony Richardson and the Indianapolis Colts.

Indianapolis Colts Vs Buffalo Bills Pre-Season Betting Odds

Team:	Spread:	Total:
Indianapolis Colts	-2.5 (-110)	O38.0 (-115)
Buffalo Bills	+2.5 (-110)	U38.0 (-105)

Sean McDermott and the Buffalo Bills are relentless in the preseason, winning nine of their last 10 games over the past three seasons. The Bills defense should handle the inexperienced Anthony Richardson, who has reported to have struggled adjusting in the NFL so far.

Bet the Bills to cover the +2.5-point spread and win outright on Saturday, August 12 at 1 p.m. ET.

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Zachary Kelley

Zach graduated from Florida State University with a degree in Writing, Editing, and Media. Zach is interested in the legalization aspect of sports betting and enjoys participating in DFS. He has a passion for sports writing and most enjoys writing about football and baseball both professional and collegiate.